In Utah, its roots run deep.
According to a health advocacy group, Utah is the most depressed state in the nation and women here are twice as likely to suffer from depression than men.
Meghan Griggs of salt lake city has struggled with depression since she was a teenager.
Griggs said, "It's almost as if someone put bricks on your chest."
She says it's a constant sadness that suppresses your desire to live, but what causes it?
Experts say depression is often caused by genetic factors, a chemical imbalance in the brain, or even dark and gloomy weather.
But trauma, extreme change, and societal pressures can also play a role.
Griggs said, "I see that, I do see that here and I don't see it elsewhere."
Griggs was born and raised here. She said in Utah, women pack on the pressure to be perfect after constant comparison to one another.
Griggs said, "When I was growing up there was that pressure in seeing the other girls and stuff like that and you could feel that pressure that they were putting on each other."
But that wasn't her story.
Griggs blames a chemical imbalance for her depression. An imbalance that led to dark and destructive behaviors.
Griggs said, "I began self medicating and I did that for a number of years using alcohol."
Now with the help of anti-depressants and a good doctor, she is slowly making the shift to sobriety.
Griggs is now a married and working mother of two.