Favors hit eight of nine shots and blocked three shots while helping the Jazz hold Boston to 44 percent shooting at EnergySolutions Arena in his first game since before the All-Star break. The Jazz center missed the previous three contests with a right hip sprain.
Forward Marvin Williams added 19 points as Utah improved to 20-36 with its first win over Boston in eight tries. No current Jazz player was on the roster the last time the team beat the Celtics, on March 22, 2010.
Forward Jeff Green and center Kelly Olynyk each scored 21 points to top Boston, and point guard Rajon Rondo, who didn't play Saturday in Sacramento, finished with 18 points and 10 assists.
However, the Celtics ended their four-game road trip without a win, falling for the fifth consecutive time. Boston, which beat Utah 97-87 at home on Nov. 6, dropped to 19-39.
The tipoff was delayed by about 10 minutes as a camera atop one of the shot clocks was repaired, and both teams started slowly once the game began.
Boston held a 5-4 lead almost three minutes into the game when Utah seized the lead for good with a 6-0 run.
Utah went ahead 27-18 after the first quarter, playing with much more energy than it did a 121-104 home loss to the Minnesota Timberwolves on Saturday.
The Jazz increased their advantage to 59-46 at halftime and eventually led by 18 points. Utah was ahead by double figures for most of the second half.
Boston looked as if it were ready to return from a long trip, which included stops (and losses) in San Antonio, Phoenix, Sacramento and Salt Lake City. The Celtics return home Wednesday to play Atlanta after not having a game at the TD Garden since Feb. 12.
Boston played without center Jared Sullinger (concussion), guard Avery Bradley (ankle) and center Vitor Faverani (knee).
Jazz guard Gordon Hayward, who played for Boston coach Brad Stevens at Butler from 2008-10, only hit four of 11 shots to finish with eight points as his slump continued. He did dish out eight assists, though.
Jazz guard Trey Burke had 12 points, five rebounds and three assists in his first matchup against Rondo. Burke was out with a broken finger when the teams met in November.