A tsunami warning was issued following the quake, which was centered 49 miles west-northwest of Iquique, Chile, and was 6.21 miles deep, the USGS said.
The Pacific Tsunami Warning Center said a 6-foot tsunami that hit Pisagua, Chile, at 8:04 p.m. ET. No damage assessment has been made at this time.
ABC News producer Helen Hughes in Santiago, Chile, said there is a tsunami alert for all of Chile, Peru and Ecuador. Evacuation orders have been issued for the cities of Arica, Iquique and Antofagasta. All cities are along a low coast, and each has a significant climb to higher land further inland, Hughes said.
There have been numerous quakes in the same area over the past few weeks.